The latest study researching the human body’s response to Malaria has informed that the antibodies are initially made in response to infections in mucous membranes i.e, lungs, intestines or vagina amongst malaria patients.
High Levels of IgA Antibodies Found In Adult Malaria Patients
As per the researchers from the University of Maryland, the study provides new data into how a human body reponds ot malaria infection. It is to find new ways to treat the infection and develop vaccines accordingly.
The study published by the NPJ vaccines, the team looked at the antibodies that was collected from the blood samples taken from the 54 adult research participants after they were infected with malaria in the laboratory. They were infected either via IV inserted directly or via mosquito bites.
ALSO READ: Long-Covid symptoms may be caused by fatigue: Study
The study also included 47 children in Mali, West Africa who were enrolled in the vaccine trial for malaria and got infected with the same during the study period.
During the study, the researchers found out that the levels of IgA antibodies were high in adult malaria patients.
Andrea Berry, Associate Professor of Paediatrics at the varsity’s school of medicine said that they don’t know what exactly the triggers the IgA antibodies to develop but they believe that it happens early during the malaria infection. He said that there are several possibilities of differences between the adults and the children.
Children and Adult Respond Differently To Malaria Infection
Berry said that the immune system of children responds differently to the paradise than the adults. So it is possible that the IgA antibodies are only created during the early stages of Malaria infection. She explained that with the adult patients, they knew that they were being infected with Malaria for the first time. But the same with children was unknown.
Meanwhile, the time of the infection with the adult patients was uniform. But the children getting infected with malaria during the time of the study was coincidental.
